Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9684748 | 0.85 | RAB9A (0.54) | RAB9AL3MBTL1SMN1; SMN2POLBHTT | |
| SCHEMBL9683933 | 0.77 | MAPT (0.54) | RAB9ASMN1; SMN2POLBHTTALDH1A1 | |
| SCHEMBL9683945 | 0.76 | MAPT (0.54) | RAB9ASMN1; SMN2POLBHTTALDH1A1 | |
| SCHEMBL9684465 | 0.75 | MAPT (0.51) | SMN1; SMN2HTTALDH1A1NPC1KMT2A | |
| SCHEMBL10600006 | 0.74 | RAB9A (0.81) | RAB9AL3MBTL1SMN1; SMN2POLBHTT | |
| SCHEMBL9683960 | 0.70 | GRK6 (0.49) | L3MBTL1POLBHTTALDH1A1NPC1 | |
| SCHEMBL13986150 | 0.69 | RAB9A (0.52) | RAB9AL3MBTL1SMN1; SMN2POLBHTT | |
| SCHEMBL9685946 | 0.68 | KEAP1 (0.51) | RAB9AL3MBTL1SMN1; SMN2POLBHTT | |
| SCHEMBL10490777 | 0.68 | RAB9A (1.00) | RAB9AL3MBTL1SMN1; SMN2POLBHTT | |
| SCHEMBL20695012 | 0.68 | RAB9A (0.60) | RAB9AL3MBTL1POLBHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5144028-A | Antibiotics | MERCK & CO., INC. (US) | 1992-09-01 | — | — | US | disclosed |
| EP-0469844-A1 | 2-(9-fluorenonyl)-carbapenem | MERCK & CO. INC. (US) | 1992-02-05 | — | — | EP | disclosed |
| US-5025007-A | 2-(9-fluorenonyl)-carbapenem antibacterial agents | MERCK & CO., INC. (US) | 1991-06-18 | — | — | US | disclosed |