Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 4/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | S100A4 | P26447 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9684489 | 0.97 | PTPRC (0.49) | PTPRCCASP3SMN1; SMN2ALDH1A1ATM | |
| SCHEMBL31065274 | 0.88 | PTPRC (0.57) | PTPRCCASP3SMN1; SMN2ALDH1A1ATM | |
| SCHEMBL25260739 | 0.88 | PTPRC (0.57) | PTPRCCASP3SMN1; SMN2ALDH1A1ATM | |
| SCHEMBL11846453 | 0.84 | PTPRC (0.60) | PTPRCCASP3SMN1; SMN2ALDH1A1ATM | |
| SCHEMBL13550874 | 0.84 | PTPRC (0.60) | PTPRCCASP3SMN1; SMN2ALDH1A1ATM | |
| SCHEMBL9769408 | 0.84 | PTPRC (0.60) | PTPRCCASP3SMN1; SMN2ALDH1A1ATM | |
| SCHEMBL9769488 | 0.84 | PTPRC (0.60) | PTPRCCASP3SMN1; SMN2ALDH1A1ATM | |
| SCHEMBL9684565 | 0.83 | NPC1 (0.45) | PTPRCALDH1A1ATMMAPTNPC1 | |
| SCHEMBL9684470 | 0.82 | HTR7 (0.46) | PTPRCSMN1; SMN2ALDH1A1ATMMAPT | |
| SCHEMBL26120300 | 0.82 | S100A4 (0.62) | PTPRCCASP3SMN1; SMN2ALDH1A1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5144028-A | Antibiotics | MERCK & CO., INC. (US) | 1992-09-01 | — | — | US | disclosed |
| EP-0469844-A1 | 2-(9-fluorenonyl)-carbapenem | MERCK & CO. INC. (US) | 1992-02-05 | — | — | EP | disclosed |
| US-5025007-A | 2-(9-fluorenonyl)-carbapenem antibacterial agents | MERCK & CO., INC. (US) | 1991-06-18 | — | — | US | disclosed |