Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 4/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | DRD3 | P35462 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD5 | P21918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9685609 | 0.91 | DRD2 (0.39) | HTR2CSIGMAR1CA2DRD2DRD3 | |
| SCHEMBL9684037 | 0.89 | S1PR1 (0.38) | HTR2CSIGMAR1CA2ADRA2AADRA2B | |
| SCHEMBL9684023 | 0.87 | KDM4E (0.35) | — | |
| SCHEMBL7761425 | 0.86 | GRIA2 (0.31) | GRIA2 | |
| SCHEMBL9437722 | 0.86 | SIGMAR1 (0.36) | HTR2BSIGMAR1HTR2A | |
| Hydrochloric Acid SCHEMBL9437889 | 0.84 | SIGMAR1 (0.37) | HTR2BSIGMAR1HTR2A | |
| Hydrochloric Acid SCHEMBL8871802 | 0.84 | LMNA (0.38) | ADRA2ADRD2DRD3DRD1DRD4 | |
| SCHEMBL8109679 | 0.83 | MAPT (0.41) | SIGMAR1ADRA2AADRA2BADRA2CDRD2 | |
| SCHEMBL7760492 | 0.83 | — | — | |
| SCHEMBL9449597 | 0.82 | SIGMAR1 (0.55) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084469-A | Analgesics | ADIR ET COMPAGNIE (FR) | 1992-01-28 | — | — | US | disclosed |