SCHEMBL9685502

SCHEMBL9685502

CCOP(=O)(CCC(COn1cnc2c(Cl)ncnc21)CO[Si](C)(C)C(C)(C)C)OCC

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.34
P2RY1 P47900 1/20 0.31
HSP90AA1 P07900 1/20 0.30
HSP90AB1 P08238 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9683433 0.89 FAP (0.35) HSP90AA1HSP90AB1
SCHEMBL9684065 0.86 FDPS (0.34) FDPSHSP90AA1HSP90AB1
SCHEMBL9857662 0.79 ABCB11 (0.35) FDPSHSP90AA1HSP90AB1
SCHEMBL9685495 0.77 FDPS (0.33) FDPS
SCHEMBL9683414 0.76 ABCB11 (0.36) HSP90AA1HSP90AB1
SCHEMBL9685082 0.76 ABCB11 (0.35) HSP90AA1HSP90AB1
SCHEMBL9683381 0.75 FDPS (0.42) FDPSHSP90AA1HSP90AB1
SCHEMBL9683394 0.74 FDPS (0.41) FDPSHSP90AA1HSP90AB1
SCHEMBL9684215 0.74 ADORA2A (0.40)
SCHEMBL9857669 0.73 ABCB11 (0.36) FDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5166198-A Herpes virus infections BEECHAM P.L.C. (GB) 1992-11-24 US disclosed