SCHEMBL9684186

SCHEMBL9684186

CCOP(=O)(CCCOn1cnc2c(Cl)nc(NC=O)nc21)OCC

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTK2 Q05397 1/20 0.33
BTK Q06187 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9685074 0.97 PTK2 (0.31) PTK2BTK
SCHEMBL9857532 0.90
SCHEMBL9417258 0.87
SCHEMBL9675616 0.86
SCHEMBL9683777 0.80 KDM4E (0.31)
SCHEMBL9683381 0.79 FDPS (0.42) PTK2
SCHEMBL10497045 0.79
SCHEMBL8742510 0.79 CTSL (0.33)
SCHEMBL9677690 0.78 ACHE (0.30)
SCHEMBL9187929 0.77 ACHE (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0374622-A2 3,4-Bis-(methylamino)-6-(2,3-dimethyl-2-butyl)-1,2,4-triazin-5(4H)-one, process for its preparation and its use as a herbicide BAYER AG (DE) 1990-06-27 EP claimed
US-5166198-A Herpes virus infections BEECHAM P.L.C. (GB) 1992-11-24 US disclosed
EP-0404296-A1 Phosphono derivatives of purine with antiviral activity Beecham Group p.l.c. (GB) 1990-12-27 EP disclosed
EP-0374622-A2 3,4-Bis-(methylamino)-6-(2,3-dimethyl-2-butyl)-1,2,4-triazin-5(4H)-one, process for its preparation and its use as a herbicide BAYER AG (DE) 1990-06-27 EP disclosed