Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9629766 | 0.81 | KMT2A (0.40) | ALDH1A1LMNAMAPTPOLBL3MBTL1 | |
| SCHEMBL13954243 | 0.80 | VDR (0.51) | VDRALDH1A1DHODHLMNAMAPT | |
| SCHEMBL8061919 | 0.77 | VDR (0.47) | VDRALDH1A1LMNACYP2C9CYP2C19 | |
| SCHEMBL2890 | 0.76 | CA9 (0.53) | VDRALDH1A1LMNAMAPTCYP2C9 | |
| Ammonia Solution, Strong SCHEMBL9470841 | 0.74 | CA9 (0.51) | VDRALDH1A1LMNAMAPTCYP2C9 | |
| Toluene SCHEMBL9257721 | 0.74 | CA9 (0.51) | VDRALDH1A1LMNAMAPTCYP2C9 | |
| SCHEMBL6859827 | 0.73 | CA2 (0.63) | VDRALDH1A1MAPTCYP2C9CYP2C19 | |
| SCHEMBL8052920 | 0.73 | CA2 (0.63) | VDRALDH1A1MAPTCYP2C9CYP2C19 | |
| SCHEMBL5870619 | 0.73 | MEN1 (0.54) | VDRALDH1A1KDM4EHPGDKEAP1 | |
| SCHEMBL11743502 | 0.73 | ALDH1A1 (0.46) | VDRALDH1A1LMNAMAPTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134147-A | Antipsychotic agents | ADIR ET COMPAGNIE (FR) | 1992-07-28 | — | — | US | disclosed |
| US-5100902-A | Dopamine and Serotonin Antagonists, Antipsychotic Agents | ADIR ET COMPAGNIE (FR) | 1992-03-31 | — | — | US | disclosed |