Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.45 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.45 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9684692 | 0.79 | AGTR1 (0.48) | AGTR1AGTR2ABCC4ABCB11PDE3B | |
| SCHEMBL9683853 | 0.76 | AGTR1 (0.52) | AGTR1AGTR2 | |
| SCHEMBL9684439 | 0.75 | AGTR1 (0.48) | AGTR1AGTR2ABCC4ABCB11PDE3B | |
| SCHEMBL352 | 0.71 | AGTR1 (0.64) | AGTR1AGTR2 | |
| SCHEMBL984922 | 0.70 | AGTR1 (0.63) | AGTR1AGTR2 | |
| SCHEMBL201 | 0.70 | AGTR1 (0.63) | AGTR1AGTR2 | |
| SCHEMBL11100306 | 0.70 | AGTR1 (0.72) | AGTR1AGTR2 | |
| SCHEMBL276 | 0.70 | AGTR1 (0.60) | AGTR1AGTR2 | |
| SCHEMBL8580231 | 0.69 | AGTR2 (0.52) | AGTR1AGTR2 | |
| SCHEMBL3874586 | 0.69 | AGTR1 (0.61) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0485929-A1 | Substituted azoles, process for their preparation and their application | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-05-20 | — | — | EP | disclosed |