Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.38 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.37 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL379146 | 0.91 | TDP1 (0.56) | ALDH1A1TDP1TSHRSMN1; SMN2LMNA | |
| Vinylsulfonic Acid SCHEMBL28173703 | 0.90 | TDP1 (0.45) | ALDH1A1TDP1TSHRSMN1; SMN2LMNA | |
| Styrene SCHEMBL8087550 | 0.89 | ALDH1A1 (0.58) | ALDH1A1TDP1TSHRSMN1; SMN2LMNA | |
| Vinylsulfonic Acid SCHEMBL28148853 | 0.88 | TDP1 (0.43) | ALDH1A1TDP1TSHRSMN1; SMN2LMNA | |
| Sulfuric Acid SCHEMBL8445673 | 0.86 | TRIM24 (0.52) | ALDH1A1SMN1; SMN2LMNAKMT2AMEN1 | |
| Sulfuric Acid SCHEMBL3091932 | 0.85 | ACHE (0.49) | ALDH1A1SMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL2438058 | 0.84 | TDP1 (0.43) | ALDH1A1TDP1TSHRSMN1; SMN2SLC9A1 | |
| Sulfuric Acid SCHEMBL713715 | 0.84 | ALDH1A1 (0.50) | ALDH1A1TDP1TSHRSMN1; SMN2LMNA | |
| SCHEMBL473080 | 0.83 | ALDH1A1 (0.63) | ALDH1A1TDP1TSHRLMNAKMT2A | |
| SCHEMBL7638 | 0.83 | ALDH1A1 (0.63) | ALDH1A1TDP1TSHRLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9056955-B2 | Resin particle comprising microparticle made of a crystalline resin, and method for producing the same | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 2015-06-16 | — | — | US | disclosed |
| US-20110020741-A1 | RESIN PARTICLE AND METHOD FOR PRODUCING THE SAME | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 2011-01-27 | — | — | US | disclosed |