Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9685692 | 0.75 | TSHR (0.33) | — | |
| Hydrochloric Acid SCHEMBL9685643 | 0.73 | KMT2A (0.39) | CYP2C9KMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL18891796 | 0.67 | APLNR (0.39) | KMT2AMEN1CTSK | |
| SCHEMBL28047111 | 0.66 | CTSK (0.41) | CTSK | |
| SCHEMBL18878390 | 0.66 | CTSL (0.39) | KMT2AMEN1CTSK | |
| SCHEMBL28083977 | 0.63 | P2RX7 (0.41) | KMT2ACTSKALDH1A1 | |
| SCHEMBL24052174 | 0.63 | CA12 (0.43) | KMT2AMEN1CTSK | |
| SCHEMBL7397628 | 0.63 | ATM (0.44) | KMT2AMEN1CTSKALDH1A1HTT | |
| SCHEMBL9750048 | 0.63 | CTSK (0.44) | KMT2ACTSK | |
| SCHEMBL10669320 | 0.63 | CTSK (0.44) | KMT2ACTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091425-A | Inhibitors of the catalytic action of renin | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-02-25 | — | — | US | disclosed |