Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9684553 | 1.00 | SRC (0.43) | SRCMAPTLMNAALDH1A1MAPK1 | |
| SCHEMBL9684457 | 0.97 | SRC (0.41) | SRCMAPTLMNAALDH1A1MAPK1 | |
| SCHEMBL9684460 | 0.97 | SRC (0.41) | SRCMAPTLMNAALDH1A1MAPK1 | |
| SCHEMBL9685915 | 0.79 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL9684483 | 0.76 | ALDH1A1 (0.35) | MAPTLMNAALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL29117498 | 0.69 | ELANE (0.55) | MAPTLMNAALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL24045960 | 0.69 | MAPK1 (0.42) | MAPTLMNAALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL9685863 | 0.69 | MAPT (0.36) | MAPTLMNAALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL9685859 | 0.69 | MAPT (0.36) | MAPTLMNAALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL9684489 | 0.68 | PTPRC (0.49) | MAPTLMNAALDH1A1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5144028-A | Antibiotics | MERCK & CO., INC. (US) | 1992-09-01 | — | — | US | disclosed |
| EP-0469844-A1 | 2-(9-fluorenonyl)-carbapenem | MERCK & CO. INC. (US) | 1992-02-05 | — | — | EP | disclosed |
| US-5025007-A | 2-(9-fluorenonyl)-carbapenem antibacterial agents | MERCK & CO., INC. (US) | 1991-06-18 | — | — | US | disclosed |