Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.33 |
| ▸ | ALDH1A3 | P47895 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.32 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.32 |
| ▸ | ABAT | P80404 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9684483 | 0.97 | ALDH1A1 (0.35) | ALDH1A1TSHRCYP2A6TYRKDM4E | |
| SCHEMBL27878197 | 0.79 | MAOA (0.46) | ALDH1A1TSHRCYP2A6TYRKDM4E | |
| SCHEMBL9684553 | 0.79 | SRC (0.43) | ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL9684551 | 0.79 | SRC (0.43) | ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL9684457 | 0.76 | SRC (0.41) | ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL9684460 | 0.76 | SRC (0.41) | ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL29117498 | 0.76 | ELANE (0.55) | ALDH1A1TSHRKDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL7551452 | 0.76 | MEN1 (0.50) | ALDH1A1TSHRKDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL9849269 | 0.74 | ELANE (0.53) | ALDH1A1TSHRKDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL2372163 | 0.74 | MEN1 (0.52) | ALDH1A1TSHRCYP2A6KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5144028-A | Antibiotics | MERCK & CO., INC. (US) | 1992-09-01 | — | — | US | disclosed |
| EP-0469844-A1 | 2-(9-fluorenonyl)-carbapenem | MERCK & CO. INC. (US) | 1992-02-05 | — | — | EP | disclosed |
| US-5025007-A | 2-(9-fluorenonyl)-carbapenem antibacterial agents | MERCK & CO., INC. (US) | 1991-06-18 | — | — | US | disclosed |