Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9685915 | 0.97 | ALDH1A1 (0.37) | ALDH1A1ELANETSHRMAOAMAOB | |
| SCHEMBL27878197 | 0.80 | MAOA (0.46) | ALDH1A1ELANETSHRMAOAMAOB | |
| SCHEMBL9684460 | 0.80 | SRC (0.41) | ALDH1A1SMN1; SMN2LMNAMAPTMAPK1 | |
| SCHEMBL9684457 | 0.80 | SRC (0.41) | ALDH1A1SMN1; SMN2LMNAMAPTMAPK1 | |
| SCHEMBL9849269 | 0.79 | ELANE (0.53) | ALDH1A1ELANETSHRMAOARAB9A | |
| SCHEMBL6253115 | 0.77 | NPC1 (0.50) | ALDH1A1ELANETSHRMAOARAB9A | |
| SCHEMBL29117498 | 0.77 | ELANE (0.55) | ALDH1A1ELANETSHRMAOAMAOB | |
| SCHEMBL7551452 | 0.77 | MEN1 (0.50) | ALDH1A1ELANETSHRMAOARAB9A | |
| SCHEMBL9684553 | 0.76 | SRC (0.43) | ALDH1A1SMN1; SMN2LMNAMAPTMAPK1 | |
| SCHEMBL9684551 | 0.76 | SRC (0.43) | ALDH1A1SMN1; SMN2LMNAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5144028-A | Antibiotics | MERCK & CO., INC. (US) | 1992-09-01 | — | — | US | disclosed |
| EP-0469844-A1 | 2-(9-fluorenonyl)-carbapenem | MERCK & CO. INC. (US) | 1992-02-05 | — | — | EP | disclosed |
| US-5025007-A | 2-(9-fluorenonyl)-carbapenem antibacterial agents | MERCK & CO., INC. (US) | 1991-06-18 | — | — | US | disclosed |