Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 10/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9683757 | 0.92 | ADRB2 (0.50) | ADRB2HIF1ATSHRADRB1ADRB3 | |
| SCHEMBL9683704 | 0.89 | ALDH1A1 (0.44) | ADRB2TSHRRAB9AADRB1ADRB3 | |
| SCHEMBL9684696 | 0.89 | ALDH1A1 (0.44) | ADRB2TSHRRAB9AADRB1ADRB3 | |
| SCHEMBL9683619 | 0.89 | ALDH1A1 (0.44) | ADRB2TSHRRAB9AADRB1ADRB3 | |
| SCHEMBL9684731 | 0.89 | ADRB2 (0.44) | ADRB2HIF1ATSHRRAB9AADRB1 | |
| SCHEMBL9684785 | 0.89 | ADRB2 (0.44) | ADRB2HIF1ATSHRRAB9AADRB1 | |
| SCHEMBL9684954 | 0.87 | THRB (0.52) | ADRB2TSHRRAB9AADRB3HTR1A | |
| SCHEMBL9684978 | 0.86 | CYP2D6 (0.52) | ADRB2HIF1ATSHRRAB9ASLC6A3 | |
| SCHEMBL9683608 | 0.84 | XBP1 (0.47) | TSHRRAB9ALMNAKDM4EGAA | |
| SCHEMBL9683717 | 0.84 | ALDH1A1 (0.48) | ADRB2HIF1ATSHRRAB9AADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128369-A | Antiallergens, bronchodilator agents | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-07-07 | — | — | US | disclosed |
| EP-0404197-A2 | Arylalkylamine derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1990-12-27 | — | — | EP | disclosed |