Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 16/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11317135 | 0.86 | PTGIR (0.48) | PTGIRCYP2C9PTGER4PTGER2GSK3B | |
| SCHEMBL9033376 | 0.81 | GSK3B (0.49) | CYP4F2CYP4A11GSK3B | |
| SCHEMBL7496572 | 0.80 | KDM5A (0.43) | PTGIRHTTGSK3B | |
| SCHEMBL7006107 | 0.77 | NPSR1 (0.37) | CYP4F2CYP4A11GSK3B | |
| SCHEMBL4768685 | 0.74 | MAPK10 (0.42) | — | |
| SCHEMBL6656904 | 0.73 | MMP2 (0.52) | GSK3B | |
| SCHEMBL823438 | 0.73 | ALDH1A1 (0.46) | PTGIRHTT | |
| SCHEMBL626277 | 0.73 | TARBP2 (0.48) | HTT | |
| SCHEMBL12138862 | 0.72 | SMN1; SMN2 (0.45) | PTGIR | |
| SCHEMBL155151 | 0.72 | KDM4E (0.38) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0485929-A1 | Substituted azoles, process for their preparation and their application | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-05-20 | — | — | EP | disclosed |