Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 3/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31301099 | 0.84 | ALDH1A1 (0.54) | ALDH1A1LMNATHRBMAOBMAOA | |
| SCHEMBL4499439 | 0.84 | ALDH1A1 (0.54) | ALDH1A1LMNATHRBMAOBMAOA | |
| SCHEMBL9685852 | 0.79 | ALDH1A1 (0.49) | ALDH1A1LMNATHRBMAOBMAOA | |
| SCHEMBL13601005 | 0.78 | ALDH1A1 (0.48) | ALDH1A1LMNATHRBMAOBMAOA | |
| SCHEMBL28657395 | 0.77 | MAOB (0.48) | ALDH1A1LMNATHRBMAOBMAOA | |
| SCHEMBL24756156 | 0.75 | POLB (0.42) | ALDH1A1LMNATHRBMAOBMAOA | |
| SCHEMBL24756395 | 0.75 | POLB (0.42) | ALDH1A1LMNATHRBMAOBMAOA | |
| SCHEMBL24755738 | 0.75 | POLB (0.42) | ALDH1A1LMNATHRBMAOBMAOA | |
| SCHEMBL178528 | 0.75 | CYP2D6 (0.50) | ALDH1A1LMNATHRBMAOBMAOA | |
| SCHEMBL10368234 | 0.74 | FLT3 (0.52) | ALDH1A1LMNATHRBMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990008545-A1 | LIPOXYGENASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1990-08-09 | — | — | WO | claimed |
| US-5175183-A | Antiinflammatory agents, respiratory system disorders | ABBOTT LABORATORIES (US) | 1992-12-29 | — | — | US | disclosed |
| WO-1990008545-A1 | LIPOXYGENASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1990-08-09 | — | — | WO | disclosed |