Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4499439 | 0.81 | ALDH1A1 (0.54) | ALDH1A1LMNATHRBMAOBMAOA | |
| SCHEMBL31301099 | 0.81 | ALDH1A1 (0.54) | ALDH1A1LMNATHRBMAOBMAOA | |
| SCHEMBL9684715 | 0.78 | ALDH1A1 (0.51) | ALDH1A1LMNATHRBMAOBMAOA | |
| SCHEMBL16347541 | 0.78 | SMN1; SMN2 (0.46) | ALDH1A1LMNATHRBMAOBMAOA | |
| SCHEMBL4495518 | 0.77 | MAPT (0.53) | ALDH1A1LMNAPOLBMAPTMEN1 | |
| SCHEMBL13600942 | 0.77 | MAPT (0.53) | ALDH1A1LMNAPOLBMAPTMEN1 | |
| SCHEMBL9685852 | 0.76 | ALDH1A1 (0.49) | ALDH1A1LMNATHRBMAOBMAOA | |
| SCHEMBL28657395 | 0.74 | MAOB (0.48) | ALDH1A1LMNATHRBMAOBMAOA | |
| SCHEMBL4518064 | 0.72 | CNR2 (0.48) | LMNAMAPTMEN1KMT2ANPC1 | |
| SCHEMBL4518068 | 0.72 | CNR2 (0.48) | LMNAMAPTMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7638540-B2 | Benzofuran compound and medicinal composition containing the same | THE NEW INDUSTRY RESEARCH ORGANIZATION (JP) | 2009-12-29 | — | — | US | disclosed |
| US-7638540-B2 | Benzofuran compound and medicinal composition containing the same | THE NEW INDUSTRY RESEARCH ORGANIZATION (JP) | 2009-12-29 | — | — | US | disclosed |