Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MAOA | P21397 | 4/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | TTR | P02766 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9423356 | 0.78 | S100A4 (0.57) | MAPTMAOAALDH1A1TTRMAOB | |
| SCHEMBL9683960 | 0.76 | GRK6 (0.49) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL8954279 | 0.76 | PTPRC (0.50) | MAPTMEN1KMT2AMAOAAURKA | |
| SCHEMBL9684529 | 0.75 | ALDH1A1 (0.40) | MAPTMEN1KMT2AMAOAALDH1A1 | |
| SCHEMBL9684783 | 0.75 | MAPT (0.37) | MAPTMEN1KMT2AMAOAAURKA | |
| SCHEMBL9685886 | 0.75 | CDC25B (0.42) | MAPTMEN1KMT2AMAOAAURKA | |
| SCHEMBL9684787 | 0.75 | SOAT1 (0.39) | MAPTMEN1KMT2AMAOAAURKA | |
| SCHEMBL9685937 | 0.75 | MAPT (0.46) | MAPTMEN1KMT2AALDH1A1TTR | |
| SCHEMBL5350497 | 0.74 | MAPT (0.52) | MAPTMEN1KMT2AMAOAAURKA | |
| SCHEMBL9685946 | 0.74 | KEAP1 (0.51) | MAPTMEN1KMT2AALDH1A1TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5105679-A | — | — | None | — | — | JP | disclosed |
| US-5356889-A | Carbapenicillins | MERCK & CO., INC. (US) | 1994-10-18 | — | — | US | disclosed |
| JP-H05105679-A | 2-(9-FLUORENONYL)-CARBAPENEM ANTIBACTERIAL AGENT | MERCK & CO INC | 1993-04-27 | — | — | JP | disclosed |
| US-5144028-A | Antibiotics | MERCK & CO., INC. (US) | 1992-09-01 | — | — | US | disclosed |
| EP-0472306-A1 | 2-(9-fluorenonyl)-carbapenem antibacterial agents | MERCK & CO. INC. (US) | 1992-02-26 | — | — | EP | disclosed |
| EP-0469844-A1 | 2-(9-fluorenonyl)-carbapenem | MERCK & CO. INC. (US) | 1992-02-05 | — | — | EP | disclosed |
| US-5034384-A | Bactericides, antibiotics for resistant bacteria | MERCK & CO., INC. (US) | 1991-07-23 | — | — | US | disclosed |
| US-5025007-A | 2-(9-fluorenonyl)-carbapenem antibacterial agents | MERCK & CO., INC. (US) | 1991-06-18 | — | — | US | disclosed |