Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | APAF1 | O14727 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 3/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.43 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.43 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | CDC25B | P30305 | 3/20 | 0.42 |
| ▸ | TDP2 | O95551 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9684982 | 0.89 | MAPT (0.55) | ALDH1A1MAPTKDM4EAPAF1LMNA | |
| SCHEMBL10897976 | 0.75 | ALDH1A1 (0.57) | ALDH1A1MAPTKDM4ELMNASMN1; SMN2 | |
| SCHEMBL13649357 | 0.74 | MAPT (0.59) | ALDH1A1MAPTKDM4EAPAF1LMNA | |
| SCHEMBL15765912 | 0.74 | MEN1 (0.50) | ALDH1A1MAPTKDM4EAPAF1LMNA | |
| Anthraquinone SCHEMBL7856851 | 0.74 | MEN1 (0.57) | ALDH1A1MAPTKDM4EAPAF1LMNA | |
| SCHEMBL14307223 | 0.74 | CDC25B (0.50) | ALDH1A1MAPTKDM4EAPAF1LMNA | |
| SCHEMBL29036676 | 0.73 | FGFR1 (0.45) | ALDH1A1MAPTKDM4EAPAF1LMNA | |
| SCHEMBL28669771 | 0.73 | MAPT (0.50) | ALDH1A1MAPTKDM4EAPAF1LMNA | |
| SCHEMBL9178142 | 0.73 | APAF1 (0.48) | ALDH1A1MAPTKDM4EAPAF1LMNA | |
| Anthraquinone SCHEMBL11698233 | 0.73 | MEN1 (0.71) | ALDH1A1MAPTKDM4EAPAF1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145975-A | Parasiticides | THE ROCKEFELLER UNIVERSITY (US) | 1992-09-08 | — | — | US | disclosed |
| US-4942170-A | PARASITICIDES, ANTIPROTOZOA AGENTS | THE ROCKEFELLER UNIVERSITY (US) | 1990-07-17 | — | — | US | disclosed |
| EP-0355279-A2 | Use of nitrogen-containing compounds as antiparasitics, and compositions containing them | DRUG & VACCINE DEVELOPMENT CORPORATION (US) | 1990-02-28 | — | — | EP | disclosed |