Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9208886 | 0.79 | IDH1 (0.39) | ADRA1DLMNATSHR | |
| SCHEMBL7767403 | 0.73 | — | — | |
| SCHEMBL9686053 | 0.72 | PTGS1 (0.38) | PTGS1PTGS2CDK2TDP1ALDH1A1 | |
| SCHEMBL29152299 | 0.66 | PTGS1 (0.51) | PTGS1PTGS2TDP1ALDH1A1HPGD | |
| SCHEMBL9449402 | 0.66 | SIGMAR1 (0.51) | POLB | |
| SCHEMBL8785466 | 0.65 | DRD2 (0.46) | ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL7854317 | 0.65 | DRD2 (0.40) | — | |
| SCHEMBL7759822 | 0.64 | SIGMAR1 (0.48) | KMT2APOLB | |
| SCHEMBL7761424 | 0.64 | SIGMAR1 (0.46) | TDP1MAPTMEN1KMT2AGAA | |
| SCHEMBL7763028 | 0.64 | SIGMAR1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084469-A | Analgesics | ADIR ET COMPAGNIE (FR) | 1992-01-28 | — | — | US | disclosed |