Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9686135 | 0.79 | IDH1 (0.38) | — | |
| SCHEMBL9686026 | 0.75 | LTA4H (0.35) | HTR6MAPTALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL8109679 | 0.72 | MAPT (0.41) | LMNAHTR6MAPTHSD17B10HPGD | |
| SCHEMBL9684915 | 0.72 | PARP1 (0.38) | PTGS1PTGS2LMNATDP1MAPT | |
| SCHEMBL8114240 | 0.72 | KDM4E (0.37) | PTGS1LMNATDP1MAPTHSD17B10 | |
| SCHEMBL7761425 | 0.72 | GRIA2 (0.31) | — | |
| Hydrochloric Acid SCHEMBL8870609 | 0.71 | MAPT (0.43) | LMNAHTR6MAPTHSD17B10HPGD | |
| Hydrochloric Acid SCHEMBL8871802 | 0.71 | LMNA (0.38) | PTGS1LMNATDP1MAPTHSD17B10 | |
| SCHEMBL9684037 | 0.70 | S1PR1 (0.38) | PTGS1PTGS2LMNAHTR6HSD17B10 | |
| SCHEMBL7760492 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084469-A | Analgesics | ADIR ET COMPAGNIE (FR) | 1992-01-28 | — | — | US | disclosed |