Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 4/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.42 |
| ▸ | CES2 | O00748 | 7/20 | 0.41 |
| ▸ | CES1 | P23141 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11573012 | 0.87 | ALDH1A1 (0.50) | RAB9AEGFRERBB2ALDH1A1TSHR | |
| SCHEMBL1665573 | 0.85 | TSHR (0.50) | RAB9AEGFRERBB2CES2CES1 | |
| SCHEMBL6243535 | 0.83 | MAPT (0.44) | RAB9AEGFRERBB2ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL8038931 | 0.81 | MAPT (0.43) | RAB9AEGFRERBB2ALDH1A1TSHR | |
| SCHEMBL10690897 | 0.81 | EGFR (0.57) | RAB9AEGFRERBB2CES2CES1 | |
| SCHEMBL4538369 | 0.80 | HPGD (0.56) | RAB9AEGFRERBB2ALDH1A1TDP1 | |
| SCHEMBL13253174 | 0.79 | ALDH1A1 (0.60) | ALDH1A1TSHRTDP1MEN1MAPT | |
| SCHEMBL21082740 | 0.79 | LTA4H (0.47) | RAB9ACES2CES1ALDH1A1TSHR | |
| SCHEMBL21082726 | 0.79 | SRD5A2 (0.50) | EGFRERBB2CES2CES1ALDH1A1 | |
| SCHEMBL13253683 | 0.79 | PLK1 (0.50) | EGFRERBB2ALDH1A1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5164512-A | Triarylimidazole derivative, determination of hydrogen peroxide generated by enzymatic reaction | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1992-11-17 | — | — | US | disclosed |
| EP-0404526-A1 | Oxidizable color producing reagent | WAKO PURE CHEMICAL INDUSTRIES LTD (JP) | 1990-12-27 | — | — | EP | disclosed |