Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8724168 | 0.91 | SRD5A2 (0.49) | TSHRTP53SRD5A2CA2CA1 | |
| SCHEMBL19831260 | 0.89 | NPC1 (0.60) | TSHRTP53CA2CA1CA12 | |
| SCHEMBL1230226 | 0.88 | RARB (0.47) | TSHRTP53SRD5A2CA2CA1 | |
| SCHEMBL9685025 | 0.85 | RAB9A (0.44) | TSHRMEN1POLBKMT2AEGFR | |
| SCHEMBL11573012 | 0.85 | ALDH1A1 (0.50) | TSHRSRD5A2MEN1NPC1KMT2A | |
| SCHEMBL472319 | 0.83 | TSHR (0.55) | TSHRTP53SRD5A2CA2CA1 | |
| SCHEMBL4538369 | 0.82 | HPGD (0.56) | SRD5A2MEN1NPC1KMT2AEGFR | |
| SCHEMBL6243535 | 0.82 | MAPT (0.44) | TSHRTP53MEN1NPC1POLB | |
| SCHEMBL472318 | 0.82 | HCAR3 (0.57) | TSHRTP53CA2CA12CA9 | |
| SCHEMBL766052 | 0.82 | EGFR (0.61) | TSHRTP53SRD5A2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8329383-B2 | Negative-working lithographic printing plate precursors | EASTMAN KODAK COMPANY (US) | 2012-12-11 | — | — | US | claimed |
| EP-2496416-A2 | NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSORS | Eastman Kodak Company (US) | 2012-09-12 | — | — | EP | claimed |
| WO-2011056905-A2 | NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSORS | EASTMAN KODAK COMPANY (US) | 2011-05-12 | — | — | WO | claimed |
| US-20110104450-A1 | NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSORS | BANK OF AMERICA, N.A., AS AGENT | 2011-05-05 | — | — | US | claimed |
| CN-113603647-B | PARP inhibitor-alkylation bifunctional molecule and preparation method and application thereof | 潍坊医学院 | 2023-01-31 | — | — | CN | disclosed |
| CN-113603647-A | PARP inhibitor-alkylation bifunctional molecule and preparation method and application thereof | 潍坊医学院 | 2021-11-05 | — | — | CN | disclosed |
| CN-108409608-B | Aromatic nitrogen mustard histone deacetylase inhibitor and preparation method and application thereof | 潍坊医学院 | 2020-11-03 | — | — | CN | disclosed |
| US-9622991-B2 | Hematopoietic growth factor mimetic small molecule compounds and their uses | LIGAND PHARMACEUTICALS INC. (US) | 2017-04-18 | — | — | US | disclosed |
| US-9144557-B2 | Hematopoietic growth factor mimetic small molecule compounds and their uses | LIGAND PHARMACEUTICALS INC. (US) | 2015-09-29 | — | — | US | disclosed |
| US-20150252043-A1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | CITIBANK, N.A., AS ADMINISTRATIVE AGENT | 2015-09-10 | — | — | US | disclosed |
| US-20140243324-A1 | USE OF HEMATOPOIETIC GROWTH FACTOR MIMETICS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2014-08-28 | — | — | US | disclosed |
| EP-2642994-A2 | USE OF HEMATOPOIETIC GROWTH FACTOR MIMETICS | Ligand Pharmaceuticals Incorporated (US) | 2013-10-02 | — | — | EP | disclosed |
| US-20120295904-A1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | LIGAND PHARMACEUTICALS INC. (US) | 2012-11-22 | — | — | US | disclosed |
| EP-2496416-A2 | NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSORS | Eastman Kodak Company (US) | 2012-09-12 | — | — | EP | disclosed |
| EP-2488486-A1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | Ligand Pharmaceuticals Inc. (US) | 2012-08-22 | — | — | EP | disclosed |
| WO-2012068406-A2 | USE OF HEMATOPOIETIC GROWTH FACTOR MIMETICS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2012-05-24 | — | — | WO | disclosed |
| WO-2011056905-A2 | NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSORS | EASTMAN KODAK COMPANY (US) | 2011-05-12 | — | — | WO | disclosed |
| US-20110104450-A1 | NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSORS | BANK OF AMERICA, N.A., AS AGENT | 2011-05-05 | — | — | US | disclosed |
| WO-2011046954-A1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | LIGAND PHARMACEUTICALS INC. (US) | 2011-04-21 | — | — | WO | disclosed |
| US-6620864-B2 | With a plasticizer, a catalyst for hardening by ring opening, a catalyst for hardening by light and as accelerator a p-aminobenzoic acid alkyl ester, N,N-disubstituted by hydroxyalkyl groups; free of contraction and adhesiveness | LSP DENTAL CHEMISTRY AG (CH) | 2003-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140243324-A1 | USE OF HEMATOPOIETIC GROWTH FACTOR MIMETICS | HGF, EPOR, MPL | TSHR 1674/4885TP53 828/4885SRD5A2 3475/4885 |
| US-20150252043-A1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | MPL, CSF3R, HGF | TSHR 1185/4885TP53 309/4885SRD5A2 4000/4885 |
| US-20120295904-A1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | MPL, CSF3R, HGF | TSHR 1185/4885TP53 309/4885SRD5A2 4000/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.