Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.57 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.57 |
| ▸ | ESRRG | P62508 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9320631 | 0.90 | EGFR (0.53) | EGFRERBB2ESRRGRAB9AHCAR3 | |
| SCHEMBL8700270 | 0.88 | EGFR (0.48) | EGFRERBB2ESRRGRAB9AHCAR3 | |
| SCHEMBL2498524 | 0.88 | EGFR (0.57) | EGFRERBB2ESRRGRAB9AHCAR3 | |
| SCHEMBL472318 | 0.86 | HCAR3 (0.57) | EGFRERBB2ESRRGRAB9AHCAR3 | |
| SCHEMBL22926070 | 0.86 | MAPT (0.57) | EGFRERBB2ESRRGRAB9AHCAR3 | |
| SCHEMBL2369922 | 0.85 | EGFR (0.53) | EGFRERBB2RAB9ACNR2CES2 | |
| SCHEMBL9321329 | 0.84 | EGFR (0.54) | EGFRERBB2ESRRGRAB9AHCAR3 | |
| SCHEMBL6338168 | 0.83 | EGFR (0.51) | EGFRERBB2ESRRGHCAR3CNR2 | |
| SCHEMBL1306139 | 0.83 | MAPT (0.58) | ESRRGRAB9AL3MBTL1MEN1POLB | |
| SCHEMBL7150414 | 0.82 | EGFR (0.47) | EGFRERBB2ESRRGRAB9ACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4760006-A | Photoconductive layer containing photoconductor, a binder and a sensitizing dyestuff on electroconductive support | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-07-26 | — | — | US | disclosed |
| EP-0166230-B1 | 2,3-BIS(DIALKYLAMINOPHENYL)QUINOXALINES AND THEIR USE IN ELECTROGRAPHIC RECORDING MATERIALS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-04-06 | — | — | EP | disclosed |
| EP-0166230-A1 | 2,3-Bis(dialkylaminophenyl)quinoxalines and their use in electrographic recording materials | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-01-02 | — | — | EP | disclosed |