Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 4/20 | 0.45 |
| ▸ | DRD4 | P21917 | 3/20 | 0.45 |
| ▸ | DRD3 | P35462 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 3/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.42 |
| ▸ | TUBB | P07437 | 3/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9684170 | 0.88 | MEN1 (0.51) | MEN1KMT2ALMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL3835784 | 0.85 | ACHE (0.43) | MEN1KMT2ACHRNA7LMNASMN1; SMN2 | |
| SCHEMBL8938377 | 0.76 | MEN1 (0.62) | MEN1KMT2ALMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL8938380 | 0.75 | MEN1 (0.61) | MEN1KMT2ALMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL10067337 | 0.74 | CHRNA7 (0.56) | MEN1KMT2ACHRNA7LMNASMN1; SMN2 | |
| SCHEMBL28455949 | 0.72 | MEN1 (0.58) | MEN1KMT2ALMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL10067334 | 0.70 | DRD2 (0.51) | KMT2ACHRNA7LMNADRD2DRD4 | |
| SCHEMBL3096663 | 0.69 | KMT2A (0.52) | MEN1KMT2ACHRNA7LMNASMN1; SMN2 | |
| SCHEMBL8938441 | 0.69 | MEN1 (0.54) | MEN1KMT2ALMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL2343474 | 0.69 | TUBB4A (0.57) | MEN1KMT2AKDM4ETUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5124327-A | Administering in the prevention and treatment of AIDS | MERCK & CO., INC. (US) | 1992-06-23 | — | — | US | disclosed |