Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7439167 | 0.83 | PLOD2 (0.50) | ALDH1A1SMN1; SMN2KMT2ACYP3A4MEN1 | |
| SCHEMBL6817570 | 0.77 | MEN1 (0.58) | ALDH1A1SMN1; SMN2ALOX12KMT2AHPGD | |
| SCHEMBL9799560 | 0.77 | TSHR (0.63) | ALDH1A1SMN1; SMN2KMT2AHPGDCYP3A4 | |
| SCHEMBL2026026 | 0.77 | TSHR (0.63) | ALDH1A1SMN1; SMN2KMT2AHPGDCYP3A4 | |
| SCHEMBL12375171 | 0.76 | ALDH1A1 (0.71) | ALDH1A1SMN1; SMN2ALOX12KMT2AHPGD | |
| SCHEMBL2874488 | 0.74 | KMT2A (0.59) | ALDH1A1SMN1; SMN2KMT2AHPGDCYP3A4 | |
| SCHEMBL4576240 | 0.74 | MEN1 (0.54) | ALDH1A1SMN1; SMN2ALOX12KMT2AHPGD | |
| SCHEMBL1945591 | 0.73 | MTNR1A (0.59) | ALDH1A1SMN1; SMN2ALOX12KMT2AHPGD | |
| SCHEMBL11216066 | 0.73 | MEN1 (0.62) | ALDH1A1SMN1; SMN2ALOX12KMT2AHPGD | |
| SCHEMBL18179454 | 0.73 | KMT2A (0.52) | ALDH1A1SMN1; SMN2KMT2AHPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091425-A | Inhibitors of the catalytic action of renin | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-02-25 | — | — | US | disclosed |