Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.41 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9685970 | 0.87 | SGMS2 (0.44) | SMN1; SMN2ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL9687634 | 0.87 | SGMS2 (0.44) | SMN1; SMN2ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL9686652 | 0.85 | SGMS2 (0.46) | SMN1; SMN2MEN1LMNAKMT2ASGMS2 | |
| SCHEMBL9686346 | 0.84 | KMT2A (0.52) | SMN1; SMN2ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL9691940 | 0.81 | SHMT2 (0.59) | SMN1; SMN2ALDH1A1HSD17B10LMNASHMT2 | |
| SCHEMBL9686367 | 0.80 | NPC1 (0.57) | SMN1; SMN2MEN1KMT2ASGMS2NPSR1 | |
| SCHEMBL9685596 | 0.80 | SGMS2 (0.44) | SMN1; SMN2MEN1KMT2ASGMS2SHMT2 | |
| SCHEMBL9687740 | 0.80 | METAP1 (0.43) | SMN1; SMN2MEN1KMT2ASGMS2SHMT2 | |
| SCHEMBL9686420 | 0.80 | SGMS2 (0.47) | SMN1; SMN2HSD17B10MEN1LMNAKMT2A | |
| SCHEMBL9686954 | 0.79 | ATM (0.42) | SMN1; SMN2MEN1LMNAKMT2ASGMS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268989-B1 | IMIDAZOPYRIDINE COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-07-08 | — | — | EP | disclosed |
| US-4831041-A | ANTIULCER AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-05-16 | — | — | US | disclosed |
| EP-0268989-A1 | Imidazopyridine compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-06-01 | — | — | EP | disclosed |