Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | RAF1 | P04049 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.38 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9687740 | 0.90 | METAP1 (0.43) | SGMS2SHMT2LTA4HMAPK14L3MBTL1 | |
| SCHEMBL9687429 | 0.85 | KMT2A (0.46) | ATMPKML3MBTL1KDM4EMEN1 | |
| SCHEMBL9687634 | 0.83 | SGMS2 (0.44) | ATMSGMS2SHMT2TDP1LTA4H | |
| SCHEMBL9685970 | 0.83 | SGMS2 (0.44) | ATMSGMS2SHMT2LTA4HMAPK14 | |
| SCHEMBL9686652 | 0.83 | SGMS2 (0.46) | SGMS2KDRSHMT2TDP1LTA4H | |
| SCHEMBL9685699 | 0.79 | SMN1; SMN2 (0.53) | ATMSGMS2SHMT2TDP1LTA4H | |
| SCHEMBL9687613 | 0.78 | L3MBTL1 (0.42) | ATMAURKBEGFRRAF1KDR | |
| SCHEMBL9685596 | 0.78 | SGMS2 (0.44) | SGMS2EGFRKDRSHMT2TDP1 | |
| SCHEMBL9686949 | 0.77 | TSHR (0.43) | ATMAURKBEGFRRAF1KDR | |
| SCHEMBL9686367 | 0.77 | NPC1 (0.57) | SGMS2TDP1LTA4HMAPK14L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268989-B1 | IMIDAZOPYRIDINE COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-07-08 | — | — | EP | disclosed |
| US-4831041-A | ANTIULCER AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-05-16 | — | — | US | disclosed |
| EP-0268989-A1 | Imidazopyridine compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-06-01 | — | — | EP | disclosed |