Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.43 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.42 |
| ▸ | TDP2 | O95551 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9686954 | 0.90 | ATM (0.42) | METAP1SGMS2LTA4HMAPK14NPC1 | |
| SCHEMBL9686652 | 0.90 | SGMS2 (0.46) | SGMS2LTA4HMAPK14NPC1RAB9A | |
| SCHEMBL9685596 | 0.85 | SGMS2 (0.44) | SGMS2LTA4HMAPK14NPC1RAB9A | |
| SCHEMBL9686263 | 0.84 | KMT2A (0.48) | METAP1NPC1RAB9AHTTSMN1; SMN2 | |
| SCHEMBL9685970 | 0.84 | SGMS2 (0.44) | SGMS2LTA4HMAPK14NPC1RAB9A | |
| SCHEMBL9687634 | 0.84 | SGMS2 (0.44) | SGMS2LTA4HMAPK14NPC1RAB9A | |
| SCHEMBL9686367 | 0.83 | NPC1 (0.57) | SGMS2LTA4HMAPK14NPC1RAB9A | |
| SCHEMBL9686420 | 0.81 | SGMS2 (0.47) | SGMS2MAPK14RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL9685699 | 0.80 | SMN1; SMN2 (0.53) | SGMS2LTA4HMAPK14NPC1RAB9A | |
| SCHEMBL10561420 | 0.78 | LTA4H (0.39) | SGMS2LTA4HMAPK14NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268989-B1 | IMIDAZOPYRIDINE COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-07-08 | — | — | EP | disclosed |
| US-4831041-A | ANTIULCER AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-05-16 | — | — | US | disclosed |
| EP-0268989-A1 | Imidazopyridine compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-06-01 | — | — | EP | disclosed |