Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.69 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.69 |
| ▸ | HTR1A | P08908 | 4/20 | 0.46 |
| ▸ | HTR2C | P28335 | 4/20 | 0.46 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | IDH1 | O75874 | 1/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.41 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MPI | P34949 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9686038 | 0.83 | ALDH1A1 (0.51) | PDE3BPDE3AHTR1AHTR2CMAPT | |
| SCHEMBL1848088 | 0.82 | PDE3B (1.00) | PDE3BPDE3APSMB8SMN1; SMN2MAPT | |
| SCHEMBL9685980 | 0.82 | SMN1; SMN2 (0.55) | PDE3BPDE3AHTR1AHTR2CSMN1; SMN2 | |
| SCHEMBL9205683 | 0.81 | HTR1A (0.53) | PDE3BPDE3AHTR1AHTR2CMAPT | |
| SCHEMBL9685648 | 0.80 | CMA1 (0.56) | PDE3BPDE3AHTR1AHTR2CMAPT | |
| SCHEMBL9685722 | 0.80 | PDE3B (0.76) | PDE3BPDE3APSMB8SMN1; SMN2MAPT | |
| SCHEMBL7761677 | 0.79 | PDE3B (0.56) | PDE3BPDE3AHTR1AHTR2CSLC2A1 | |
| SCHEMBL27318309 | 0.79 | PDE3B (0.56) | PDE3BPDE3AHTR1AHTR2CPSMB8 | |
| SCHEMBL20777399 | 0.77 | GAA (0.51) | LTA4HSLC2A1PTPN5SAE1UBA2 | |
| SCHEMBL30832803 | 0.77 | GAA (0.51) | LTA4HSLC2A1PTPN5SAE1UBA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084469-A | Analgesics | ADIR ET COMPAGNIE (FR) | 1992-01-28 | — | — | US | disclosed |