Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10435332 | 0.70 | — | — | |
| SCHEMBL8853322 | 0.69 | THRB (0.32) | THRB | |
| SCHEMBL9564288 | 0.69 | THRB (0.32) | THRB | |
| SCHEMBL9564289 | 0.69 | — | — | |
| SCHEMBL11547903 | 0.67 | — | — | |
| SCHEMBL9564304 | 0.65 | LMNA (0.38) | CYP2C19LMNATHRB | |
| SCHEMBL28599727 | 0.63 | CYP2C19 (0.32) | CYP2C19LMNA | |
| SCHEMBL430265 | 0.63 | LMNA (0.32) | CYP2C19LMNA | |
| SCHEMBL5968815 | 0.63 | LMNA (0.36) | CYP2C19LMNACYP3A4 | |
| SCHEMBL397414 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5132444-A | Converting haloethane-, hydroxyethane- or esterified hydroxyethanephosphonic ester; solid catalyst consisting of phosphate, acid oxide or acid oxide support impregnated with acidic substance, alkali metal oxide or alkaline earth oxide | BASF AKTIENGESELLSCHAFT (DE) | 1992-07-21 | — | — | US | disclosed |
| EP-0013744-B1 | CATALYST AND PROCESS FOR THE POLYMERIZATION OF ALPHA-OLEFINS AND A PROCESS FOR PREPARING AN ALPHA-OLEFIN POLYMERIZATION CATALYST COMPONENT | Standard Oil Company (US) | 1984-11-07 | — | — | EP | disclosed |
| US-4233182-A | High activity catalyst for the polymerization of alpha-olefins | STANDARD OIL COMPANY (INDIANA) (US) | 1980-11-11 | — | — | US | disclosed |
| US-4233253-A | Method for the preparation of metal salts of phosphorus acid esters | STANDARD OIL COMPANY (INDIANA) (US) | 1980-11-11 | — | — | US | disclosed |
| EP-0013744-A1 | Catalyst and process for the polymerization of alpha-olefins and a process for preparing an alpha-olefin polymerization catalyst component | Standard Oil Company (US) | 1980-08-06 | — | — | EP | disclosed |