SCHEMBL9564288

SCHEMBL9564288

CC(Cl)(Cl)OP(C)(=O)OC(C)(Cl)Cl

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.32
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8853322 0.80 THRB (0.32) THRBTSHR
SCHEMBL9564289 0.79
SCHEMBL4253621 0.76
SCHEMBL10435332 0.75
SCHEMBL5968815 0.73 LMNA (0.36) TSHR
SCHEMBL9564304 0.69 LMNA (0.38) THRB
SCHEMBL10891152 0.69
SCHEMBL9685791 0.69 CYP2C19 (0.38) THRB
SCHEMBL537766 0.67 THRB (0.32) THRBTSHR
SCHEMBL575804 0.67 ACHE (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0523991-A1 High resiliency polyurethane foams with improved static fatigue ARCO CHEMICAL TECHNOLOGY, INC. (US) 1993-01-20 EP disclosed
US-5157056-A Contains phosphorous compounds ARCO CHEMICAL TECHNOLOGY, L.P. (US) 1992-10-20 US disclosed