SCHEMBL9685813

SCHEMBL9685813

[CH2]c1c(C)cccc1NC(=O)OC(C)(C)C

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LCK P06239 3/20 0.45
RXFP1 Q9HBX9 1/20 0.44
BRD9 Q9H8M2 1/20 0.43
LMNA P02545 1/20 0.42
POLB P06746 1/20 0.42
METAP1 P53582 1/20 0.41
NLRP3 Q96P20 1/20 0.40
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA9 Q16790 1/20 0.39
ALDH1A1 P00352 1/20 0.39
HPGD P15428 1/20 0.39
BRD4 O60885 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9685897 0.85 L3MBTL1 (0.43) LMNAPOLBALDH1A1HPGD
SCHEMBL1534089 0.83 NPC1 (0.58) RXFP1BRD9LMNAPOLBNPC1
SCHEMBL5839856 0.83 HPGD (0.49) LMNAPOLBNLRP3NPC1RAB9A
SCHEMBL17931854 0.81 LCK (0.45) LCKRXFP1BRD9LMNAPOLB
SCHEMBL1006923 0.81 LCK (0.45) LCKRXFP1BRD9LMNAPOLB
SCHEMBL28856066 0.81 RXFP1 (0.47) LCKRXFP1BRD9LMNAPOLB
SCHEMBL21681358 0.81 LCK (0.46) LCKRXFP1BRD9LMNAPOLB
SCHEMBL29493510 0.81 LCK (0.45) LCKRXFP1BRD9LMNAPOLB
SCHEMBL3984461 0.80 KDM4E (0.51) LCKRXFP1BRD9LMNAPOLB
SCHEMBL2880191 0.79 LMNA (0.54) RXFP1BRD9LMNAPOLBMETAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0268989-B1 IMIDAZOPYRIDINE COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-07-08 EP claimed
US-4831041-A ANTIULCER AGENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1989-05-16 US claimed
EP-0268989-A1 Imidazopyridine compounds and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1988-06-01 EP claimed
CN-1159806-A Imidazopyridine-pyrrolidones and imidazopyridine-oxazolidinones BYK GULDEN LOMBERG CHEM FAB (DE) 1997-09-17 CN disclosed
EP-0268989-B1 IMIDAZOPYRIDINE COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-07-08 EP disclosed
US-4831041-A ANTIULCER AGENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1989-05-16 US disclosed
EP-0268989-A1 Imidazopyridine compounds and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1988-06-01 EP disclosed