Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CTSA | P10619 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9687873 | 0.91 | ALDH1A1 (0.42) | CYP1A2ALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL25300109 | 0.82 | CYP1A2 (0.43) | CYP1A2ALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL16571594 | 0.78 | CYP1A2 (0.41) | CYP1A2ALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL21884142 | 0.77 | CYP1A2 (0.50) | CYP1A2ALDH1A1KDM4ELMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL17984662 | 0.76 | ALDH1A1 (0.40) | CYP1A2ALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL9688059 | 0.75 | ALDH1A1 (0.42) | ALDH1A1KDM4ELMNAPOLBMAPT | |
| SCHEMBL577637 | 0.69 | POLB (0.53) | CYP1A2ALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL578033 | 0.69 | CYP1A2 (0.41) | CYP1A2ALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL8404026 | 0.69 | ALDH1A1 (0.64) | CYP1A2ALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL1006385 | 0.69 | CYP1A2 (0.53) | CYP1A2ALDH1A1KDM4ELMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0484750-A1 | Substituted sulfonylaminotriazolylpyrimidines | BAYER AG (DE) | 1992-05-13 | — | — | EP | disclosed |