Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 5/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9687873 | 0.83 | ALDH1A1 (0.42) | ALDH1A1KMT2AMEN1HTTPOLB | |
| SCHEMBL108078 | 0.82 | P2RX7 (0.36) | ALDH1A1KMT2AMEN1POLBGAA | |
| SCHEMBL9685817 | 0.75 | CYP1A2 (0.42) | ALDH1A1KMT2AHTTPOLBNPC1 | |
| SCHEMBL10626117 | 0.73 | HTT (0.45) | ALDH1A1KMT2AMEN1HTTPOLB | |
| Hydrochloric Acid SCHEMBL10628171 | 0.71 | HTT (0.43) | ALDH1A1KMT2AMEN1HTTPOLB | |
| SCHEMBL6454723 | 0.67 | P2RX7 (0.62) | KMT2AMEN1MAPTP2RX7NOS3 | |
| SCHEMBL6450016 | 0.67 | P2RX7 (0.54) | ALDH1A1GAANPC1PKMP2RX7 | |
| SCHEMBL22804462 | 0.67 | MAPT (0.48) | ALDH1A1KMT2AMEN1POLBGAA | |
| SCHEMBL949243 | 0.65 | GAA (0.45) | ALDH1A1KMT2AMEN1POLBAPOBEC3G | |
| SCHEMBL1179224 | 0.64 | GAA (0.37) | ALDH1A1KMT2AMEN1HTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0484750-A1 | Substituted sulfonylaminotriazolylpyrimidines | BAYER AG (DE) | 1992-05-13 | — | — | EP | disclosed |