Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9685817 | 0.91 | CYP1A2 (0.42) | ALDH1A1LMNAMAPTHIF1ANPSR1 | |
| SCHEMBL9688059 | 0.83 | ALDH1A1 (0.42) | ALDH1A1LMNAMAPTHTTKMT2A | |
| Hydrochloric Acid SCHEMBL17984719 | 0.79 | ALDH1A1 (0.47) | ALDH1A1LMNAMAPTHIF1ANPSR1 | |
| SCHEMBL25300109 | 0.74 | CYP1A2 (0.43) | ALDH1A1LMNAMAPTNPSR1HTT | |
| SCHEMBL9461179 | 0.73 | ALDH1A1 (0.58) | ALDH1A1LMNAMAPTHIF1ANPSR1 | |
| SCHEMBL6694248 | 0.73 | ALDH1A1 (0.57) | ALDH1A1LMNAMAPTHIF1ANPSR1 | |
| SCHEMBL882663 | 0.71 | CYP1A2 (0.52) | ALDH1A1LMNAMAPTHIF1ANPSR1 | |
| SCHEMBL9847096 | 0.71 | HTT (0.54) | ALDH1A1LMNAMAPTHIF1ANPSR1 | |
| SCHEMBL7013053 | 0.71 | ALDH1A1 (0.50) | ALDH1A1LMNAMAPTHIF1ANPSR1 | |
| SCHEMBL16571594 | 0.70 | CYP1A2 (0.41) | ALDH1A1LMNACYP1A2KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0484750-A1 | Substituted sulfonylaminotriazolylpyrimidines | BAYER AG (DE) | 1992-05-13 | — | — | EP | disclosed |