Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874248 | 0.85 | TP53 (0.34) | TP53PKMTRPA1GRIN1GRIN2B | |
| SCHEMBL9686841 | 0.77 | GRIN1 (0.43) | PKMMAPTSMN1; SMN2GRIN1GRIN2B | |
| SCHEMBL9687641 | 0.76 | TMEM97 (0.34) | TP53PKMLMNAKDM4EL3MBTL1 | |
| SCHEMBL9687690 | 0.75 | GRM7 (0.36) | — | |
| SCHEMBL27300218 | 0.72 | POLB (0.34) | PKMMAPTSMN1; SMN2KDM4E | |
| SCHEMBL9687715 | 0.70 | — | — | |
| SCHEMBL9537457 | 0.67 | CNR2 (0.38) | — | |
| SCHEMBL4682441 | 0.65 | TP53 (0.32) | TP53MAPTSMN1; SMN2 | |
| SCHEMBL9875039 | 0.64 | SMN1; SMN2 (0.43) | PKMSMN1; SMN2GRIN1GRIN2BLMNA | |
| SCHEMBL9686573 | 0.63 | GRIN1 (0.42) | MAPTSMN1; SMN2GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0296416-B1 | BENZO-ANELLATED CYCLIC COMPOUNDS | NIHON BAYER AGROCHEM K.K. (JP) | 1992-07-29 | — | — | EP | disclosed |
| US-5077401-A | Herbicides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1991-12-31 | — | — | US | disclosed |
| US-4902335-A | Benzo-fused cyclic compounds | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1990-02-20 | — | — | US | disclosed |
| EP-0296416-A1 | Benzo-anellated cyclic compounds | NIHON BAYER AGROCHEM K.K. (JP) | 1988-12-28 | — | — | EP | disclosed |