Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9687690 | 0.81 | GRM7 (0.36) | — | |
| SCHEMBL9874248 | 0.79 | TP53 (0.34) | TP53KMT2AKDM4EPKML3MBTL1 | |
| SCHEMBL9686547 | 0.78 | GRIN1 (0.37) | TMEM97 | |
| SCHEMBL9686590 | 0.77 | LMNA (0.30) | LMNAKMT2A | |
| SCHEMBL9837325 | 0.76 | TMEM97 (0.36) | TMEM97ADRA2AADRA2BADRA2CHRH1 | |
| SCHEMBL9839357 | 0.76 | SHMT2 (0.39) | TMEM97KDM4EADRA2AADRA2BADRA2C | |
| SCHEMBL9685828 | 0.76 | TP53 (0.35) | TP53LMNAKDM4EPKML3MBTL1 | |
| SCHEMBL9837580 | 0.72 | TMEM97 (0.33) | TMEM97 | |
| SCHEMBL10413738 | 0.72 | SHMT2 (0.36) | TMEM97KDM4E | |
| SCHEMBL9687715 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0296416-B1 | BENZO-ANELLATED CYCLIC COMPOUNDS | NIHON BAYER AGROCHEM K.K. (JP) | 1992-07-29 | — | — | EP | disclosed |
| US-5077401-A | Herbicides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1991-12-31 | — | — | US | disclosed |
| US-4902335-A | Benzo-fused cyclic compounds | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1990-02-20 | — | — | US | disclosed |