SCHEMBL9687715

SCHEMBL9687715

O=c1sc2cc(F)c(C3N=C4CCCCC4=C3Cl)cc2n1Cc1ccon1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9687690 0.77 GRM7 (0.36)
SCHEMBL9874248 0.72 TP53 (0.34)
SCHEMBL9687641 0.72 TMEM97 (0.34)
SCHEMBL9686590 0.71 LMNA (0.30)
SCHEMBL9685828 0.70 TP53 (0.35)
SCHEMBL9685668 0.62 MAPT (0.38)
SCHEMBL10474023 0.60 SMN1; SMN2 (0.37)
SCHEMBL9687049 0.59 PTGS2 (0.39)
SCHEMBL9685792 0.57 GRM7 (0.37)
SCHEMBL9875039 0.54 SMN1; SMN2 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0296416-B1 BENZO-ANELLATED CYCLIC COMPOUNDS NIHON BAYER AGROCHEM K.K. (JP) 1992-07-29 EP disclosed
US-5077401-A Herbicides NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1991-12-31 US disclosed
US-4902335-A Benzo-fused cyclic compounds NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1990-02-20 US disclosed
EP-0296416-A1 Benzo-anellated cyclic compounds NIHON BAYER AGROCHEM K.K. (JP) 1988-12-28 EP disclosed