Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL9635938 | 0.84 | SLC6A9 (0.51) | SLC6A9HTR1ADRD2HTR2ASMN1; SMN2 | |
| SCHEMBL9684843 | 0.79 | SLC6A9 (0.64) | SLC6A9HRH1KDM4EMEN1KMT2A | |
| SCHEMBL9685926 | 0.77 | SLC6A9 (0.68) | SLC6A9SMN1; SMN2MAPTKDM4EMEN1 | |
| SCHEMBL9686512 | 0.77 | SLC6A9 (0.68) | SLC6A9SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL9635911 | 0.77 | SLC6A9 (0.68) | SLC6A9HRH1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL9636330 | 0.77 | SLC6A9 (0.68) | SLC6A9HRH1KDM4EMEN1KMT2A | |
| SCHEMBL10444904 | 0.76 | SLC6A9 (0.67) | SLC6A9SMN1; SMN2MEN1KMT2APKM | |
| SCHEMBL9537069 | 0.76 | HRH1 (0.43) | SLC6A9ADRA1AHTR1AHTR2CDRD2 | |
| SCHEMBL9634560 | 0.76 | SLC6A9 (0.67) | SLC6A9HRH1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL9537351 | 0.75 | HTR1A (0.56) | SLC6A9ACHEADRA1AHTR1AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0307014-B1 | ANTI-ALLERGIC 2-(HETEROCYCLYL ALKYL) IMIDAZO PYRIDINES AND 2-(HETEROCYCLYL ALKYL) PURINES | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-12-09 | — | — | EP | disclosed |
| EP-0307014-A1 | Anti-allergic 2-(heterocyclyl alkyl) imidazo pyridines and 2-(heterocyclyl alkyl) purines | JANSSEN PHARMACEUTICA N.V. (BE) | 1989-03-15 | — | — | EP | disclosed |