Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | S100A4 | P26447 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | PTPRC | P08575 | 2/20 | 0.41 |
| ▸ | TERT | O14746 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9685511 | 0.97 | MEN1 (0.47) | HTR7HTR2BL3MBTL1MEN1KMT2A | |
| SCHEMBL9685931 | 0.82 | PTPRC (0.47) | S100A4TTRPTPRCNPC1RAB9A | |
| SCHEMBL9684565 | 0.82 | NPC1 (0.45) | MEN1KMT2AS100A4TTRPTPRC | |
| SCHEMBL9685902 | 0.82 | S100A4 (0.42) | HTR7HTR2BL3MBTL1S100A4TTR | |
| SCHEMBL11622602 | 0.82 | TTR (0.59) | HTR7HTR2BL3MBTL1MEN1KMT2A | |
| SCHEMBL9684489 | 0.79 | PTPRC (0.49) | MEN1KMT2AS100A4PTPRCNPC1 | |
| SCHEMBL9684730 | 0.79 | TERT (0.43) | MEN1KMT2AS100A4TTRPTPRC | |
| SCHEMBL9683947 | 0.79 | S100A4 (0.41) | HTR7HTR2BS100A4TTRPTPRC | |
| SCHEMBL4931763 | 0.79 | HTR7 (0.68) | HTR7HTR2BL3MBTL1MEN1KMT2A | |
| SCHEMBL9849269 | 0.77 | ELANE (0.53) | L3MBTL1MEN1KMT2AS100A4TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5144028-A | Antibiotics | MERCK & CO., INC. (US) | 1992-09-01 | — | — | US | disclosed |
| EP-0469844-A1 | 2-(9-fluorenonyl)-carbapenem | MERCK & CO. INC. (US) | 1992-02-05 | — | — | EP | disclosed |
| US-5025007-A | 2-(9-fluorenonyl)-carbapenem antibacterial agents | MERCK & CO., INC. (US) | 1991-06-18 | — | — | US | disclosed |