Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TERT | O14746 | 2/20 | 0.44 |
| ▸ | S100A4 | P26447 | 1/20 | 0.42 |
| ▸ | PTPRC | P08575 | 6/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9684730 | 0.97 | TERT (0.43) | NPC1RAB9AATMTERTS100A4 | |
| SCHEMBL9685931 | 0.83 | PTPRC (0.47) | NPC1RAB9AATMS100A4PTPRC | |
| SCHEMBL9684470 | 0.82 | HTR7 (0.46) | NPC1RAB9AATMTERTS100A4 | |
| SCHEMBL9685902 | 0.80 | S100A4 (0.42) | NPC1RAB9AATMTERTS100A4 | |
| SCHEMBL19302481 | 0.80 | TTR (0.62) | NPC1RAB9AATMTERTS100A4 | |
| SCHEMBL30414155 | 0.80 | TTR (0.62) | NPC1RAB9AATMTERTS100A4 | |
| SCHEMBL9684489 | 0.79 | PTPRC (0.49) | NPC1RAB9AATMS100A4PTPRC | |
| SCHEMBL9685511 | 0.79 | MEN1 (0.47) | NPC1RAB9ATERTS100A4PTPRC | |
| SCHEMBL9683947 | 0.77 | S100A4 (0.41) | NPC1RAB9ATERTS100A4PTPRC | |
| SCHEMBL9849269 | 0.74 | ELANE (0.53) | NPC1RAB9AATMTERTS100A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5144028-A | Antibiotics | MERCK & CO., INC. (US) | 1992-09-01 | — | — | US | disclosed |
| EP-0469844-A1 | 2-(9-fluorenonyl)-carbapenem | MERCK & CO. INC. (US) | 1992-02-05 | — | — | EP | disclosed |
| US-5025007-A | 2-(9-fluorenonyl)-carbapenem antibacterial agents | MERCK & CO., INC. (US) | 1991-06-18 | — | — | US | disclosed |