Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | CDC25B | P30305 | 2/20 | 0.44 |
| ▸ | PTPRC | P08575 | 1/20 | 0.44 |
| ▸ | PTPRF | P10586 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | CDC25A | P30304 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | S100A4 | P26447 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9423356 | 0.84 | S100A4 (0.57) | MAPTMITFPTPRCNPC1RAB9A | |
| SCHEMBL26115802 | 0.82 | TTR (0.61) | MAPTMITFCDC25BPTPRCPTPRF | |
| SCHEMBL4920271 | 0.82 | PTGS2 (0.44) | MAPTPTPRCCASP3NPC1RAB9A | |
| SCHEMBL9423198 | 0.80 | TTR (0.55) | MAPTMITFPTPRCTSHRNPC1 | |
| SCHEMBL23199032 | 0.77 | BCL2 (0.57) | MAPTMITFMEN1KMT2ATSHR | |
| SCHEMBL26120300 | 0.75 | S100A4 (0.62) | MAPTMITFCDC25BPTPRCPTPRF | |
| SCHEMBL4921071 | 0.75 | TTR (0.61) | MAPTMITFCDC25BPTPRCPTPRF | |
| SCHEMBL9423239 | 0.75 | MAPT (0.38) | MAPTPTPRCMEN1KMT2ANPC1 | |
| SCHEMBL1712387 | 0.74 | TTR (0.61) | MAPTMITFCDC25BPTPRCPTPRF | |
| SCHEMBL2265496 | 0.73 | TTR (0.62) | MAPTMITFCDC25BPTPRCPTPRF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5144028-A | Antibiotics | MERCK & CO., INC. (US) | 1992-09-01 | — | — | US | disclosed |
| EP-0469844-A1 | 2-(9-fluorenonyl)-carbapenem | MERCK & CO. INC. (US) | 1992-02-05 | — | — | EP | disclosed |
| US-5025007-A | 2-(9-fluorenonyl)-carbapenem antibacterial agents | MERCK & CO., INC. (US) | 1991-06-18 | — | — | US | disclosed |