Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.47 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31483389 | 0.97 | NPC1 (0.51) | LMNANPC1MAOAMAOBCRBN | |
| SCHEMBL31483452 | 0.91 | ALDH1A1 (0.52) | LMNANPC1MAOAMAOBCRBN | |
| SCHEMBL9717102 | 0.82 | CA12 (0.43) | LMNANPC1MAOAMAOBCRBN | |
| SCHEMBL31483358 | 0.82 | CA12 (0.42) | NPC1TSHR | |
| SCHEMBL8421512 | 0.80 | NPC1 (0.36) | LMNANPC1MAOAMAOBCRBN | |
| SCHEMBL31483398 | 0.78 | BRD4 (0.42) | LMNANPC1MAOAMAOBTSHR | |
| SCHEMBL10757930 | 0.77 | NR5A1 (0.53) | LMNANPC1MAOAMAOBNR5A1 | |
| SCHEMBL8754519 | 0.76 | LMNA (0.51) | LMNANPC1CRBNNR5A1TP53 | |
| SCHEMBL3428777 | 0.76 | LMNA (0.52) | LMNANPC1MAOAMAOBCRBN | |
| SCHEMBL8425372 | 0.75 | ALDH1A1 (0.43) | LMNATP53TSHRMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0518769-A1 | Ethanolaminebenzoate derivative, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-12-16 | — | — | EP | disclosed |