Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.33 |
| ▸ | LMNA | P02545 | 5/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.33 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9717102 | 0.78 | CA12 (0.43) | ALDH1A1PKMGPR174LMNASMN1; SMN2 | |
| SCHEMBL31483452 | 0.78 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1LMNAMAPTCYP1A2 | |
| SCHEMBL31483389 | 0.78 | NPC1 (0.51) | ALDH1A1POLBL3MBTL1LMNATSHR | |
| SCHEMBL31483398 | 0.77 | BRD4 (0.42) | ALDH1A1POLBKDM4ELMNAHSD17B10 | |
| SCHEMBL8421285 | 0.77 | ALDH1A1 (0.49) | ALDH1A1POLBGPR174TSHRHPGD | |
| SCHEMBL9685950 | 0.75 | LMNA (0.55) | ALDH1A1LMNATSHRMAPTTP53 | |
| SCHEMBL3428777 | 0.75 | LMNA (0.52) | ALDH1A1POLBKMT2ALMNAHSD17B10 | |
| SCHEMBL10338925 | 0.74 | GPR174 (0.58) | ALDH1A1POLBKMT2APKMMEN1 | |
| SCHEMBL8423212 | 0.74 | GSTP1 (0.46) | ALDH1A1KDM4ETSHRCYP1A2 | |
| SCHEMBL31483378 | 0.71 | TSHR (0.48) | ALDH1A1POLBKMT2APKMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0845467-B1 | Silicon containing sunscreen agents, sunscreen composition containing them and their use | OREAL (FR) | 1999-10-13 | — | — | EP | disclosed |
| EP-0845467-A1 | Silicon containing sunscreen agents, and cosmetic sunscreen composition containing them | L'OREAL (FR) | 1998-06-03 | — | — | EP | disclosed |
| EP-0358584-B1 | DIORGANOPOLYSILOXANES CONTAINING FUNCTIONAL BENZAL MALONATE GROUPS | RHONE-POULENC CHIMIE (FR) | 1992-09-16 | — | — | EP | disclosed |
| EP-0358584-A1 | Diorganopolysiloxanes containing functional benzal malonate groups | RHONE-POULENC CHIMIE (FR) | 1990-03-14 | — | — | EP | disclosed |