SCHEMBL9685966

SCHEMBL9685966

Cn1c(=O)[nH]cc(F)c1=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.37
LMNA P02545 2/20 0.37
MAPT P10636 2/20 0.37
TSHR P16473 2/20 0.37
PMP22 Q01453 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
CYP19A1 P11511 1/20 0.37
THPO P40225 1/20 0.37
MTOR P42345 1/20 0.37
HTT P42858 1/20 0.37
HBB P68871 1/20 0.37
ADORA2A P29274 2/20 0.36
ADORA2B P29275 2/20 0.36
ADORA3 P0DMS8 1/20 0.34
ADORA1 P30542 1/20 0.34
CCNE2 O96020 2/20 0.33
CCNE1 P24864 2/20 0.33
CDK2 P24941 2/20 0.33
CYP3A4 P08684 1/20 0.32
BLM P54132 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14694299 0.78 ALDH1A1 (0.34) ALDH1A1LMNAMAPTTSHRPMP22
SCHEMBL19417367 0.75 ALDH1A1 (0.32) ALDH1A1LMNAMAPTTSHRPMP22
SCHEMBL221825 0.74 SLC9A1 (0.41) ALDH1A1LMNAMAPTTSHRPMP22
SCHEMBL11480635 0.73 ADORA2A (0.36) ALDH1A1LMNAMAPTTSHRPMP22
SCHEMBL25979874 0.73 ADORA2A (0.36) ALDH1A1LMNAMAPTTSHRPMP22
SCHEMBL2078821 0.73 ADORA2A (0.36) ALDH1A1LMNAMAPTTSHRPMP22
SCHEMBL11301702 0.73 ALDH1A1 (0.37) ALDH1A1LMNAMAPTTSHRPMP22
SCHEMBL16652006 0.73 ADORA2A (0.36) ALDH1A1LMNAMAPTTSHRPMP22
SCHEMBL2887322 0.73 ALDH1A1 (0.37) ALDH1A1LMNAMAPTTSHRPMP22
SCHEMBL12657637 0.72 ADORA2A (0.41) ALDH1A1LMNAMAPTTSHRPMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4695232-A1 COMPOUNDS AND PROCESSES RELATED TO FLUMETYLSULFORIM ADAMA MAKHTESHIM LTD. (IL) 2026-02-18 EP disclosed
WO-2024214047-A9 COMPOUNDS AND PROCESSES RELATED TO FLUMETHYLSULFORIM ADAMA MAKHTESHIM LTD. (IL) 2025-05-30 WO disclosed
CN-119662655-A Application of RNA molecule and composition thereof in tumor immunotherapy 武汉厚先生物医药有限公司 2025-03-21 CN disclosed
WO-2024214047-A1 COMPOUNDS AND PROCESSES RELATED TO FLUMETHYLSULFORIM ADAMA MAKHTESHIM LTD. (IL) 2024-10-17 WO disclosed
CN-117136182-A Cationic lipids based on \"God\" buffers 翻译生物公司 2023-11-28 CN disclosed
WO-2023220428-A1 COMPOSITIONS FOR EDITING ASS1 TRANSCRIPTS AND METHODS THEREOF WAVE LIFE SCIENCES LTD. (SG) 2023-11-16 WO disclosed
WO-2023220440-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF WAVE LIFE SCIENCES LTD. (SG) 2023-11-16 WO disclosed
US-11795138-B2 Process of fluorinating inorganic compounds by direct fluorination Fujian Yongjing Technology Co.,Ltd (CN) 2023-10-24 US disclosed
US-11795138-B2 Process of fluorinating inorganic compounds by direct fluorination Fujian Yongjing Technology Co.,Ltd (CN) 2023-10-24 US disclosed
CN-116916936-A Compositions and methods for delivering RNA 再生技术有限责任公司 2023-10-20 CN disclosed
US-9580553-B2 Thermally-activated self-immolative materials UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) 2017-02-28 US disclosed
US-9551724-B2 5-fluoro-uracil immunoassay SALADAX BIOMEDICAL, INC. (US) 2017-01-24 US disclosed
US-20160152573-A1 BIOORTHOGONAL METHODS AND COMPOUNDS THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) 2016-06-02 US disclosed
US-20150368403-A1 THERMALLY-ACTIVATED SELF-IMMOLATIVE MATERIALS UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) 2015-12-24 US disclosed
EP-2280281-B1 5-fluoro-uracil immunoassay SALADAX BIOMEDICAL INC (US) 2014-05-21 EP disclosed
WO-2013178545-A1 ACID CERAMIDASE INHIBITORS AND THEIR USE AS MEDICAMENTS FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) 2013-12-05 WO disclosed
EP-1846763-B1 5-FLUORO-URACIL IMMUNOASSAY SALADAX BIOMEDICAL INC (US) 2012-12-05 EP disclosed
EP-0502690-A2 Cyclopropane derivative Ajinomoto Co., Inc. (JP) 1992-09-09 EP disclosed
US-4939156-A Antitumor agents MEIJI SEIKA KAISHA, LTD. (JP) 1990-07-03 US disclosed
EP-0299413-A1 New tetramethyl-cis-diaza-bicyclo[4.2.0]octane-3,5-dione derivatives having a differentiation-inducing activity MEIJI SEIKA KAISHA LTD. (JP) 1989-01-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150368403-A1 THERMALLY-ACTIVATED SELF-IMMOLATIVE MATERIALS PARG, PAICS, LRBA ALDH1A1 2098/4885LMNA 1599/4885MAPT 215/4885
US-11795138-B2 Process of fluorinating inorganic compounds by direct fluorination AFF2, CYP4F2, AFF1 ALDH1A1 1237/4885LMNA 4746/4885MAPT 3100/4885
US-20160152573-A1 BIOORTHOGONAL METHODS AND COMPOUNDS DDT, DPYD, DNPEP ALDH1A1 735/4885LMNA 3530/4885MAPT 4477/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.