SCHEMBL9685995

SCHEMBL9685995

[SiH3]OCC(CCl)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
PKM P14618 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
TSHR P16473 1/20 0.36
SCN4A P35499 4/20 0.34
TACR1 P25103 4/20 0.34
GABBR2 O75899 2/20 0.33
GABBR1 Q9UBS5 2/20 0.33
HTR2A P28223 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
HRH1 P35367 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5598365 0.79 TSHR (0.48) CYP1A2CYP2D6PKMSMN1; SMN2NPSR1
SCHEMBL675686 0.75 CA12 (0.47) CYP1A2CYP2D6PKMSMN1; SMN2NPSR1
SCHEMBL5180270 0.72 NR1I2 (0.39) HTR2A
SCHEMBL8032906 0.71 TRPA1 (0.42) CYP1A2CYP2D6PKMSMN1; SMN2NPSR1
SCHEMBL28576347 0.71 TRPA1 (0.42) CYP1A2CYP2D6PKMSMN1; SMN2NPSR1
SCHEMBL2237751 0.71 LMNA (0.48) CYP2D6TSHRHTR2ATAAR1HRH1
SCHEMBL8791200 0.70 KDM4E (0.56) CYP2D6SMN1; SMN2
SCHEMBL6268405 0.70 TAAR1 (0.52) NPSR1TACR1TAAR1
SCHEMBL6686932 0.68 AOC3 (0.43) TSHRHTR2ATAAR1HRH1
SCHEMBL7302725 0.68 HRH1 (0.39) CYP1A2CYP2D6PKMSMN1; SMN2NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5096991-A Monomer from dihydroxy aromatic compound and haloalkylsilanol, elasticity, strength SHIN-ETSU CHEMICAL CO., LTD. (JP) 1992-03-17 US disclosed