Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 6/20 | 0.39 |
| ▸ | HTR2A | P28223 | 6/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.34 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3456972 | 0.83 | HRH1 (0.36) | HRH1HTR2ATSHRCYP19A1SMN1; SMN2 | |
| SCHEMBL11481732 | 0.83 | POLB (0.42) | HRH1HTR2APOLBSIGMAR1 | |
| SCHEMBL8014868 | 0.82 | KCNH2 (0.47) | HTR2ACYP19A1SIGMAR1 | |
| SCHEMBL5598365 | 0.81 | TSHR (0.48) | HRH1HTR2ATSHRSMN1; SMN2TAAR1 | |
| SCHEMBL5635206 | 0.79 | HRH1 (0.60) | HRH1HTR2ACYP19A1TAAR1CYP1A2 | |
| SCHEMBL8868987 | 0.79 | GABBR2 (0.58) | TSHRGABBR2GABBR1HDAC3HDAC4 | |
| SCHEMBL2010028 | 0.78 | TRPA1 (0.46) | HRH1HTR2ATSHRSMN1; SMN2TAAR1 | |
| SCHEMBL6686932 | 0.78 | AOC3 (0.43) | HRH1HTR2ATSHRTAAR1SIGMAR1 | |
| SCHEMBL18184505 | 0.78 | SIGMAR1 (0.42) | HRH1HTR2ASMN1; SMN2TAAR1CYP2D6 | |
| SCHEMBL11735752 | 0.77 | HTR2A (0.56) | HRH1HTR2ATSHRSMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0114603-A1 | Indole derivatives | MERCK PATENT GmbH (DE) | 1984-08-01 | — | — | EP | disclosed |