Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 6/20 | 0.48 |
| ▸ | PPIA | P62937 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | TYK2 | P29597 | 1/20 | 0.44 |
| ▸ | PYGL | P06737 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diflubenzuron SCHEMBL42416 | 0.91 | RAB9A (0.59) | RAB9ANPC1GAAMEN1KMT2A | |
| Diflubenzuron SCHEMBL18837607 | 0.91 | RAB9A (0.59) | RAB9ANPC1GAAMEN1KMT2A | |
| SCHEMBL9324631 | 0.89 | RAB9A (0.57) | RAB9ANPC1GAAMEN1KMT2A | |
| Diflubenzuron SCHEMBL8729691 | 0.87 | NPC1 (0.56) | RAB9ANPC1GAAMEN1KMT2A | |
| SCHEMBL10711203 | 0.87 | RAB9A (0.56) | RAB9ANPC1GAAMEN1KMT2A | |
| Diflubenzuron SCHEMBL28169066 | 0.86 | NPC1 (0.54) | RAB9ANPC1GAAMEN1KMT2A | |
| Clanfenur SCHEMBL93573 | 0.82 | RAB9A (0.50) | RAB9ANPC1GAAMEN1KMT2A | |
| SCHEMBL9688121 | 0.82 | KMT2A (0.60) | RAB9ANPC1GAAMEN1KMT2A | |
| Clanfenur SCHEMBL29356092 | 0.82 | RAB9A (0.50) | RAB9ANPC1GAAMEN1KMT2A | |
| SCHEMBL10608014 | 0.81 | MAOA (0.51) | RAB9ANPC1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166180-A | Administering diphenyl substituted (thio)carbonyl(thio)urea derivatives | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1992-11-24 | — | — | US | disclosed |
| EP-0324521-A2 | Method of treating haematologic diseases and pharmaceutical compositions to be used therefor | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1989-07-19 | — | — | EP | disclosed |