Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 4/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9684161 | 0.78 | TSHR (0.37) | KMT2ASMN1; SMN2MEN1HPGDPSMD14 | |
| SCHEMBL2616489 | 0.65 | MAPK1 (0.39) | KMT2ASMN1; SMN2HPGDMAPTLMNA | |
| SCHEMBL316689 | 0.64 | MAPT (0.57) | KMT2ASMN1; SMN2MEN1HPGDPSMD14 | |
| SCHEMBL343287 | 0.63 | TSHR (0.43) | KMT2ASMN1; SMN2MAPTLMNAPOLB | |
| SCHEMBL9700761 | 0.63 | TSHR (0.49) | KMT2ASMN1; SMN2MEN1HPGDPSMD14 | |
| SCHEMBL5583389 | 0.63 | MAPK1 (0.49) | KMT2ASMN1; SMN2MEN1HPGDMAPT | |
| SCHEMBL16975561 | 0.63 | MAPK1 (0.51) | KMT2ASMN1; SMN2MEN1MAPTLMNA | |
| SCHEMBL4715558 | 0.63 | ALDH1A1 (0.50) | KMT2ASMN1; SMN2MEN1HPGDPSMD14 | |
| SCHEMBL27382568 | 0.63 | TSHR (0.42) | KMT2ASMN1; SMN2LMNAPOLBALDH1A1 | |
| SCHEMBL3128373 | 0.62 | MAPK1 (0.47) | KMT2ASMN1; SMN2MEN1HPGDPSMD14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0491218-A1 | Benzodiazepinones | F. HOFFMANN-LA ROCHE AG (CH) | 1992-06-24 | — | — | EP | disclosed |