Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9687657 | 0.87 | HPGD (0.47) | KDM4EHPGDALOX15SMN1; SMN2MAOB | |
| SCHEMBL9694548 | 0.86 | HPGD (0.47) | KDM4EHPGDALOX15NLRP3NPC1 | |
| SCHEMBL9686499 | 0.82 | ALDH1A1 (0.57) | HPGDSMN1; SMN2NLRP3NPC1RAB9A | |
| SCHEMBL11798134 | 0.81 | NPC1 (0.58) | KDM4EHPGDSMN1; SMN2MAOBNPC1 | |
| SCHEMBL9686985 | 0.79 | LCK (0.43) | NLRP3NPC1RAB9ALMNA | |
| SCHEMBL8175962 | 0.79 | RAB9A (0.46) | HPGDNPC1RAB9ACYP1A2CYP2C9 | |
| SCHEMBL9687046 | 0.79 | KDM4E (0.48) | KDM4EHPGDALOX15SMN1; SMN2MAOB | |
| SCHEMBL9687520 | 0.78 | ALDH1A1 (0.61) | KDM4EHPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL7255889 | 0.77 | HPGD (0.54) | KDM4EHPGDALOX15SMN1; SMN2MAOB | |
| SCHEMBL8576011 | 0.77 | NLRP3 (0.46) | HPGDSMN1; SMN2NLRP3NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268989-B1 | IMIDAZOPYRIDINE COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-07-08 | — | — | EP | disclosed |
| US-4831041-A | ANTIULCER AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-05-16 | — | — | US | disclosed |
| EP-0268989-A1 | Imidazopyridine compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-06-01 | — | — | EP | disclosed |